Platform drug delivery system utilizing crystal engineering and theanine dissolution
AssigneeTheaprin Pharmaceuticals Inc.
InventorsHarry G. BRITTAIN, Philip V. FELICE
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Abstract
A platform drug delivery system and a method of improving the delivery of low solubility pharmaceuticals utilizing crystal engineering and Theanine dissolution resulting in enhanced bioactivity, dissolution rate, and solid state stability.
Claims19
A cocrystal composition comprising a theanine enantiomer or a theanine homologue, and a drug selected from the group consisting of amoxicillin, ampicillin, aripiprazole, bromocriptine, cabergoline, cefadroxil, cefdinir, cabergoline, daptomycin, diflunisal, doxorubicin, efavirenz, entacapone, epinephrine, erythromycin, febuxostat, fexofenadine, fluconazole, furosemide, hydrochlorothiazide, R-ibuprofen, irinotecan, levodopa, memantine, metronidazole, nilotinib, prednisone, sulfamethoxazole, sumatriptan, valganciclovir, zafirlukast, zidovudine, gluconate zinc, and acyclovir.
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Dependencies are inferred from the claim text.