System and method for synchronizing external compression of a limb for increased blood flow

A system, comprising:

• a first sensor configured to obtain real-time measurements regarding a cardiac cycle having a diastolic phase and systolic phase of the user;
• a second sensor configured to obtain real-time measurements of muscle contractions on the limb;
• a compression apparatus configured to apply an external compression to the limb of the user;
• and
• at least one of a processor or a controller coupled to the compression apparatus configured to control the compression apparatus to apply pressure, according to a compression sequence, to a muscle of the limb based on the real-time measurements of the cardiac cycle of the user and the real-time measurements of the muscle contractions wherein the compression sequence is synchronized to commence when both a local blood flow at the limb is in the diastolic phase and the muscle is in a non-contracted state.