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US 2021/0107856 A1Published application
Co-crystals of lithium benzoate and uses thereof
AssigneeSyneuRx International (Taiwan) Corp.
InventorsGuochuan Emil Tsai, Ching-Cheng Wang, Tien-Lan Hsieh, Yuan-Chun Lo
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Abstract
The present disclosure provides co-crystals of a lithium benzoate compound and a co-former compound of Formula (I) Also provided herein are methods of preparing the co-crystals and uses thereof in treating and/or reducing the risk for neuropsychiatric disorder (e.g., schizophrenia, psychotic disorders, depressive disorders, bipolar disorders, or neurogenerative disorders).
Claims14
A co-crystal of a lithium benzoate compound and a co-former, wherein the co-former is selected from a compound of Formula (I):
- in which
- L is alkyl, carbocyclyl, C═C, C═C C═C, C═C, or absent;
- A is alkyl, carbocyclyl, or heteroaryl;
- and
- X is O or N—B, B being H, alkyl, carbocyclyl, aryl, or heteroaryl.
2 more elements
3-9. (canceled)
Dependencies are inferred from the claim text.