Methods and compositions for treating muscle disease and disorders
AssigneePhasebio Pharmaceuticals, Inc.
InventorsLynne GEORGOPOULOS, Susan ARNOLD, David James BALLANCE
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Abstract
The present disclosure provides a method of treating muscle myopathy, including muscle dystrophies and cardiomyopathies, by administering stable, long-lasting vasoactive intestinal peptide therapeutic agents. These agents include one or more clastin-like peptides and can be administered at a low-dose.
Claims17
1-66. (canceled)
A method for slowing muscle deterioration in a patient having muscular dystrophy or cardiomyopathy comprising administering to a patient in need thereof a pharmaceutical composition comprising a VPAC2-selective Vasoactive Intestinal Peptide (VIP) and an elastin-like peptide comprising at least 90 repeating units of VPGXG (SEQ ID NO:
- 3), where X is independently selected from Val, Ala, and Gly at a ratio of about 5:3:2.
Dependencies are inferred from the claim text.