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US 2021/0069201 A1Published application
Selective p2x3 modulators
AssigneesBellus Health Cough Inc., Neomed Institute
InventorsDenis GARCEAU, Antonios MATZOURANIS, Roberto BELLINI, Kemal PAYZA, Nathalie CHAURET, Susan E. BROWNE
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Abstract
Provided herein are methods for the treatment of avoiding loss of taste response while treating a chronic cough patient with a selective P2X3 modulator.
Claims31
A method of avoiding loss of taste response while treating a chronic cough patient, the method comprising administering to the patient a therapeutically effective amount of a selective P2X3 antagonist, wherein the selective P2X3 antagonist is at least 10-fold selective for P2X3 homomeric receptor antagonism versus P2X2/3 heteromeric receptor antagonism.
Dependencies are inferred from the claim text.