Single cell gel electrophoresis

A method for screening a subject for at least a DNA-damage in relation to a predisposition for and/or a presence of a disease, wherein the method comprises the steps of:

• providing carrier plate and a liquid sample;
• wherein the liquid sample comprises cells of the subject;
• providing a gel electrophoresis device, wherein the gel electrophoresis device is capable of:
• positioning at least one carrier plate in a homogenous electrical field generated by at least one pair of electrodes;
• and
• controlling strength and direction of the electrical field generated at the position of the samples accommodated on the carrier plate;
• performing a single cell gel electrophoresis on the sample of the subject by:
• positioning the sample accommodated on the carrier plate in the generated homogenous electrical field and
• controlling strength and direction of the electrical field while the sample is positioned in the gel electrophoresis device;
• determining the DNA-damage with coefficient of variation CV of 15% or less.