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US 2021/0060342 A1Published application
Devices and methods for reducing intrathoracic pressure
AssigneeRmx, LLC
InventorAmir J. TEHRANI
Life of this patent
Estimating the term…
Abstract
Devices and methods are provided to treat acute and chronic heart failure by using one or more implantable or non-implantable sensors along with phrenic nerve stimulation to reduce intrathoracic pressure and thereby reduce pulmonary artery, atrial, and ventricular pressures leading to reduced complications and hospitalization.
Claims28
A method for treating respiratory disorders, comprising:
- sensing a subject undergoing intrinsic respiration via one or multiple sensors positioned internally or externally within the patient;
- stimulating a phrenic nerve of the subject via an electrode positioned within a subclavian vessel in proximity to the phrenic nerve at least during a portion of an exhalation and/or rest cycle to maintain the diaphragm contracted relative to a non-stimulated diaphragm during the exhalation and/or rest cycle over a sustained period of time via an electrode to increase a functional residual capacity of the subject such that the mean or average intrathoracic pressure is decreased.
A device for treating respiratory disorders, comprising:
- at least one electrode configured to be positioned intravascularly within a subclavian vessel in proximity to a phrenic nerve within a patient's body such that the at least one electrode is in electrical communication with the phrenic nerve;
- a control unit in electrical communication with the at least one electrode,
- wherein the control unit is programmed to generate and deliver an electrical stimulation signal through the at least one electrode during at least a portion of an exhalation and/or rest cycle to maintain the diaphragm contracted relative to a non-stimulated diaphragm during the exhalation and/or rest cycle over a sustained period of time to increase a functional residual capacity of the patient undergoing intrinsic respiration, and
- wherein the control unit is further programmed to deliver the electrical stimulation signal until a mean or average intrathoracic pressure as determined by the control unit is decreased.
1 more element
Dependencies are inferred from the claim text.