Multiple mosquito-borne flavivirus vaccine and use thereof in inducing neutralizing antibodies
AssigneeNational Health Research Institutes
InventorsCHING-LEN LIAO, MING-SHU HSIEH, SHU-PEI LIEN
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Abstract
The present invention relates to a peptide immunogen, comprising at least one copy of amino acid sequence RCPTTGE (called JBP). The peptide immunogen of present invention can induce an effective immune response to two or more mosquito-borne flavivirus. The present invention also provides mono/multivalent virus vaccines to protect animal against multiple mosquito-borne flavivirus infection, including diseases caused by Japanese encephalitis virus (JEV), West Nile virus (WNV), Dengue Virus (DENV), and Zika virus (ZIKV) infections.
Claims10
A peptide immunogen, comprising at least one copy of amino acid sequence RCPTTGE (SEQ ID No.1), wherein the peptide induces an antibody in response to two or more mosquito-borne flavivirus.
Dependencies are inferred from the claim text.