Nanospheres for bone fracture

Abstract

A product and method of using albumin nanoparticles for stimulating bone heal by augmenting the function or effectiveness of stem cells or precursor cells in vivo. An albumin nanoparticle suspension containing submicron albumin spheres is prepared, with the albumin spheres being capable of augmenting a function and effectiveness of stem cells or precursor cells in vivo for healing bone fractures. A predetermined amount of the albumin nanoparticle suspension is administered to a patient after an onset of a bone fracture or bone injury. A function of the stem cells or precursor cells are augmented or improved by the albumin spheres to repair cellular or tissue damage associated with a fracture bone, resulting in decreasing mortality or morbidity of the patient. The albumin spheres can be bound with fibrinogen molecules in vitro or in vivo.

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