Intracellular il-1 alpha peptide methods and compositions
AssigneeCedars-Sinai Medical Center
InventorsJargalsaikhan DAGVADORJ, Moshe ARDITI, Gantsetseg TUMURKHUU, Janet MARKMAN
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Abstract
Described herein are methods and compositions for the treatment of cancer and cancer metastasis. Methods for the reduction or prevention of cancer metastasis are also described. In particular, the present invention discloses the use of the IL-1α pro-piece peptide in the treatment cancer and cancer metastasis.
Claims23
A method of treating, reducing the likelihood of having and/or ameliorating cancer in a subject in need thereof, comprising:
- administering a therapeutically effective dosage of a pro-IL-1α peptide, a pro-IL-1α peptide mimic or both to the subject, to treat, reduce the likelihood of having, and/or ameliorate the cancer.
(canceled)
A method for reducing and/or reducing the likelihood of cancer metastasis in a subject in need thereof, comprising:
- administering a therapeutically effective dosage of a pro-IL-1α peptide, a pro-IL-1α peptide mimic or both to the subject to reduce and/or reduce the likelihood of the cancer metastasis.
(canceled)
A pharmaceutical composition, comprising:
- a therapeutically effective amount of a pro-IL-1α peptide mimic;
- and
- a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.