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US 2021/0059988 A1Published application
Pharmaceutically acceptable salts of [3-(4- {2-butyl-1-[4-(4-chloro-phenoxy)-phenyl]-1h-imidazol-4-yl} -phenoxy)-propyl]-diethyl-amine
AssigneevTv Therapeutics LLC
InventorJuan Hu
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Abstract
The present invention relates to pharmaceutically acceptable salts of [3-(4-{2-butyl-1-[4-(4-chloro-phenoxy)-phenyl]-1H-imidazol-4-yl}-phenoxy)-propyl]-diethylamine (“COMPOUND I”) useful in the treatment of RAGE mediated diseases.
Claims25
A pharmaceutically acceptable acid salt of [3-(4-{2-butyl-1-[4-(4-chlorophenoxy)phenyl]-1H-imidazol-4-yl}phenoxy)-propyl]-diethylamine, wherein the pharmaceutically acceptable acid is selected from the group consisting of:
- 4-aminosalicylic acid, fumaric acid, galactaric acid, gentisic acid, hippuric acid, hydrobromic acid, hydrochloric acid, maleic acid, L-malic acid, methane sulfonic acid, oxalic acid, phosphoric acid, saccharin, L-tartaric acid, and vanillic acid.
Dependencies are inferred from the claim text.