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US 2021/0059987 A1Published application
Composition of aminopyran derivative
AssigneeSichuan Haisco Pharmaceutical Co., Ltd.
InventorsYi MO, Honghu LI, Xing WAN, Fei YE
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Abstract
The present invention relates to a composition of a compound of general formula (A), a pharmaceutically acceptable salt or a prodrug, and a preparation method therefor.
Claims34
A pharmaceutical formulation comprising auxiliary materials and an active ingredient, the auxiliary materials comprising a neutral diluent, and the active ingredient being a compound of general formula (A) and its stereoisomer, or, a pharmaceutically acceptable salt or prodrug thereof
- R1 is each independently selected from H, F, Cl, Br or I;
- R2 is each independently selected from H, F, Cl, Br, I or C1-4 alkyl, wherein the alkyl is optionally further substituted by 0-4 substituents selected from H, F, Cl, Br or I;
- ring D is selected from a 5-membered heteroaryl ring group, wherein the heteroaryl ring group is optionally further substituted by 0-4 substituents selected from H, C1-4 alkyl, S(═O)2—C1-4 alkyl or D1, and the heteroaryl ring group contains 2 or 3 N atoms;
- D1 is each independently selected from a 5-membered heteroaryl ring group, wherein the heteroaryl ring group is optionally further substituted by 0-4 substituents selected from H or C1-4 alkyl, and the heteroaryl ring group contains 2, 3 or 4 N atoms;
- and
- n is selected from 0, 1, 2, 3, 4 or 5.
3 more elements
Dependencies are inferred from the claim text.