Percutaneous absorption preparation for treating dementia comprising donepezil
AssigneesDong-A St Co., Ltd., Km Transderm Ltd.
InventorsSun-Woo JANG, Chang-Yell SHIN, Jeong-Soo KIM, Hae-Sun KIM, Kwang-Ho CHA, Hyun-Jung KIM, Masaoki GOTO
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Abstract
A percutaneous absorption preparation is disclosed. The percutaneous absorption preparation contains donepezil for treatment of dementia, wherein the preparation includes: (a) donepezil or its pharmaceutically acceptable salt as active component, (b) propylene glycol monocaprylate as solubilizer, and (c) styrene-isoprene-styrene block copolymer (“SIS”) as adhesive. The percutaneous absorption preparation has low skin irritation and high skin penetration.
Claims9
A percutaneous absorption preparation for the treatment of dementia comprising a backing layer, a drug-containing layer, and a release liner,
- wherein the drug-containing layer of percutaneous absorption preparation for treating dementia comprises (a) donepezil or a pharmaceutically acceptable salt thereof as an active component, (b) a propylene glycol monocaprylate as solubilizer, and (c) a styrene-isoprene-styrene block copolymer.
Dependencies are inferred from the claim text.