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US 2021/0059910 A1Published application
Dispersion of fine lipid particle dispersion
AssigneeKao Corporation
InventorShunsuke TAKAGI
Life of this patent
Estimating the term…
Abstract
To provide a composition in which fine particles of solid lipid such as ceramides are emulsified and dispersed in a stable manner without being crystalized. A dispersion of fine lipid particles containing the following components (A) to (E), wherein the dispersion has a pH of 3.5 or more and 8.0 or less and the fine lipid particles have a heat of fusion of 0.30 J/g or less in a temperature range of 45° C. or more and 80° C. or less and an average particle size of less than 200 nm. (A) one or more selected from the group consisting of a sterol and a derivative thereof, (B) a lipid other than the component (A), the lipid being solid or semi-solid at 25° C., (C) an anionic surfactant, (D) a water-soluble solvent and (E) water.
Claims15
1:
- A dispersion of fine lipid particles, comprising:
- (A) at least one selected from the group consisting of a sterol and a derivative thereof, in an amount of 0.08% by mass or more and 0.6% by mass or less;
- (B) a lipid other than the component (A), the lipid being solid or semi-solid at 25° C.;
- (C) an anionic surfactant in an amount of 0.002% by mass or more and 1% by mass or less;
- (D) a water-soluble solvent in an amount of 1% by mass or more and 30% by mass or less;
- and
- (E) water,
- wherein a ratio of a total mass of the component (A) and the component (B) to a mass of the component (C), ((A+B)/C), is 0.05 or more and 6.0 or less,
- the dispersion has a pH of 3.5 or more and 8.0 or less, and
- the fine lipid particles have a heat of fusion of 0.30 J/g or less in a temperature range of 45° C. or more and 80° C. or less and an average particle size of less than 200 nm.
7 more elements
(canceled)
3:
- The dispersion of fine lipid particles according to claim 1, wherein the component (A) comprises at least one selected from the group consisting of cholesterol, phytosterol, and a derivative thereof.
4:
- The dispersion of fine lipid particles according to claim 1, wherein the component (B) comprises at least one selected from the group consisting of natural ceramide, synthetic ceramide, and an aliphatic alcohol having 12 to 30 carbon atoms.
5:
- The dispersion of fine lipid particles according to claim 1, wherein the component (C) comprises at least one selected from the group consisting of an N-acylamino acid salt and an N-acylmethyltaurine salt.
6:
- The dispersion of fine lipid particles according to claim 1, further comprising:
- (F) a nonionic surfactant.
7:
- A skin cosmetic, comprising:
- the dispersion of fine lipid particles according to claim 1.
8:
- The dispersion of fine lipid particles according to claim 1, wherein the component (A) comprises at least one selected from the group consisting of cholesterol, fatty acid cholesterol ester, fatty acid phytosterol ester, cholesterol ester of N-acylamino acid, and phytosterol ester of N-acylamino acid.
9:
- The dispersion of fine lipid particles according to claim 1, wherein the component (B) comprises at least one selected from the group consisting of ceramides, sphingosines, a fatty acid having 16 to 22 carbon atoms, and an aliphatic alcohol having 12 to 30 carbon atoms.
10:
- The dispersion of fine lipid particles according to claim 1, wherein an amount of the component (B) is 0.01% by mass or more and 5.0% by mass or less.
11:
- The dispersion of fine lipid particles according to claim 1, wherein the component (C) comprises at least one selected from the group consisting of an N-acylamino acid salt, an N-acylmethyltaurine salt, an alkyl phosphate, a polyoxyethylene alkyl ether phosphate, a fatty acid salt, an alkyl sulfate ester salt, a polyoxyethylene alkyl ether sulfate, an alkyl ether carboxylate, a dialkyl sulfosuccinate, and a diacylamino acid lysine salt.
12:
- The dispersion of fine lipid particles according to claim 1, wherein the amount of the component (C) is 0.05% by mass or more and 1.0% by mass or less.
13:
- The dispersion of fine lipid particles according to claim 1, wherein a total mass of the component (A), the component (B), and the component (C) is 0.33% by mass or more and 13.0% by mass or less.
14:
- The dispersion of fine lipid particles according to claim 1, wherein the component (D) comprises at least one selected from the group consisting of a polyhydric alcohol and a lower alcohol.
15:
- The dispersion of fine lipid particles according to claim 3, further comprising:
- (F) a nonionic surfactant.
Dependencies are inferred from the claim text.