Negative pressure wound therapy dressings with local oxygen generation for topical wound therapy and related methods

A dressing for facilitating delivery of oxygen and application of negative pressure to target tissue, the dressing comprising:

• a manifold that defines a plurality of gas passageways and is configured to allow communication of oxygen to the target tissue;
• an oxygen-generating assembly comprising:
• a container including a sidewall that defines a chamber, at least a portion of the sidewall being gas-occlusive;
• and
• an oxygen-generating material disposed within the chamber and configured to release oxygen when exposed to water;
• and
• a gas-occlusive layer configured to be disposed over the manifold and the oxygen-generating assembly and coupled to tissue surrounding the target tissue such that:
• an interior volume containing the manifold and the oxygen-generating assembly is defined between the gas-occlusive layer and the target tissue;
• and
• the gas-occlusive layer limits escape of oxygen from the interior volume between the gas-occlusive layer and the tissue surrounding the target tissue;
• wherein the oxygen-generating assembly includes one or more valves configured to permit fluid communication between the chamber and the interior volume.

A method for delivering oxygen and applying negative pressure to target tissue, the method comprising:

• coupling a dressing to the target tissue, the dressing comprising;
• a manifold that defines a plurality of gas passageways, an oxygen generating material that is configured to release oxygen when exposed to water, and
• a gas-occlusive layer to a patient's tissue such that the gas-occlusive layer is disposed over the manifold and is coupled to tissue surrounding the target tissue such that:
• an interior volume is defined between the gas-occlusive layer and the target tissue;
• and
• the gas-occlusive layer limits escape of oxygen from the interior volume between the gas-occlusive layer and the tissue surrounding the target tissue;
• and
• an oxygen-generating assembly configured to be disposed within the interior volume, the oxygen-generating assembly comprising:
• a container including a sidewall that defines a chamber, at least a portion of the sidewall being gas-occlusive;
• and
• an oxygen-generating material disposed within the chamber and configured to release oxygen when exposed to water, and
• one or more valves in fluid communication between the chamber and the interior volume, at least one of the one or more valves movable between:
• a first position;
• and
• a second position in which fluid communication between the chamber and the interior volume through the valve is more restricted than when the valve is in the first position;
• and
• reducing pressure within the interior volume.