Crystal forms of an antitumor agent and their preparation methods
AssigneeXianchang Gong
InventorXianchang Gong
Life of this patent
Estimating the term…
Abstract
The present invention provides two crystal forms of jervine and their preparation methods, and their application as antitumor agents. The preparation methods of these two crystal forms are simple, high yield and can be easily scaled to industry scale.
Claims10
The present invention provides crystal form I of jervine, wherein the characteristic peaks represented by 2 θ angle (±0.2°) are positioned at 13.5097°, 13.7117°, 17.7732°, 14.5810° in the X-ray powder diffraction pattern. The structure of jervine is as follow:
The present invention provides crystal form II of jervine, wherein the characteristic peaks represented by 2 θ angle (±0.20) are positioned at 13.6199° 13.3548° 14.6803° 15.0188° 14.4729° 20.7405° 20.9599° 17.1282° 8.8458° 16.3034° in the X-ray powder diffraction pattern.
The crystal form of chain 6, wherein the X-ray powder diffraction pattern of crystal form II is shown in FIG. 2.
Dependencies are inferred from the claim text.