A pharmaceutical formulation for intraduodenal administration comprising melevodopa and carbidopa
AssigneeChiesi Farmaceutici S.p.A.
InventorsRicardo INACIO, Mark SAUNDERS, Bhanvi MEHTA, Kathrin MUEHLHOELZL-ODOERFER, Isabel Sole FONT, Grazia CAIVANO
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Abstract
A pharmaceutical formulation for intraduodenal administration comprising melevodopa and carbidopa as active ingredients and one or more excipients. Once dispersed in an aqueous medium, melevodopa is completely dissolved, and carbidopa is present as nanoparticles.
Claims20
An aqueous pharmaceutical formulation for intraduodenal administration, comprising carbidopa and melevodopa as active ingredients in a ratio of 1:5 by weight, and one or more excipients, wherein said melevodopa is completely dissolved, and said carbidopa is present as nanoparticles having a volume diameter of 100 to 1000 nm.
Dependencies are inferred from the claim text.