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US 2020/0407707 A1Published application
Method for the preparation of nanoscale dna-encircled lipid bilayers
AssigneesTechnische UniversitäT Dresden, Helmholtz-Zentrum Dresden-Rossendorf E.V.
InventorsKarim FAHMY, Thorsten-Lars SCHMIDT, Katarina IRIC
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Abstract
The present invention relates to a method for the preparation of nanoscale nucleic acid-encircled lipid bilayers, the nanoscale nucleic acid-encircled lipid bilayers and their use.
Claims20
A minicircle-surrounded lipid bilayer at least comprising one membrane associated entity, wherein the minicircle comprises at least nucleic acids or nucleic acid analogues.
A method for preparation of minicircle-surrounded lipid bilayers comprising the steps of:
- a) providing a minicircle comprising at least double stranded nucleic acids or nucleic acid analogues,
- b) mixing of the minicircle with lipids and a membrane associated entity in a detergent,
- c) removing of the detergent, and
- d) self-assembly of the minicircle-surrounded lipid bilayer comprising the membrane associated entity.
1 more element
Dependencies are inferred from the claim text.