# US 2020/0399582 A1 · System and Method for Enabling a Single Use Wireless Sensor by Optimizing Electrical Power > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2020/0399582 A1 - Document ID: US20200399582A1 - Status: Published application - Kind: A1 - Application number: 16/605,115 - Filed: 2018-04-18 - Published: 2020-12-24 - Earliest claimed: 2017-04-28 - Assignees: GE Healthcare Bio-Sciences AB - Applicants: GE Healthcare Bio-Sciences AB - Inventors: Victor Jose; Veena B N Rao; Hanish Lakhani - Web page: https://patentgrep.com/patent/US20200399582A1 ## CPC - C12M 23/14: {Bags} - C12M 23/28: {disposable or single use} - C12M 41/00: {Means for regulation, monitoring, measurement or control, e.g. flow regulation (controlling or regulating chemical, physical or physicochemical processes B01J19/0006; heating or cooling apparatus for laboratory use B01L7/00; electro optical investigation of individual particles, flow cytometers G01N15/14; automatic analysis G01N35/00; controlling or regulating in general G06N)} - C12M 41/02: {of foam (foam prevention during gasification of liquids B01D19/02)} - C12M 41/12: {of temperature (controlling the temperature of chemical or physical processes B01J19/0013, heating or cooling apparatus for laboratory use B01L7/00)} - C12M 41/26: {of pH} - C12M 41/32: {of substances in solution} - C12M 41/34: {of gas} - C12M 41/40: {of pressure} - C12M 41/46: {of cellular or enzymatic activity or functionality, e.g. cell viability} - C12M 41/48: {Automatic or computerized control (automatic analysis G01N35/00)} - C12Q 1/02: involving viable microorganisms - H02J 7/855: {with circuits adapted for supplying loads from the battery} - C12M: APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; {APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS} - C12Q: MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS (immunoassay G01N33/53); COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES - H02J: ELECTRIC POWER NETWORKS; CIRCUIT ARRANGEMENTS OR SYSTEMS FOR SUPPLYING OR DISTRIBUTING ELECTRIC POWER; SYSTEMS FOR STORING ELECTRIC ENERGY ## Abstract A system for enabling a wireless single use sensing sub-system by optimizing electrical power is presented. The system includes the sensing sub-system configured to be employed in a bio process environment. Further, the sensing sub-system includes a sensing unit configured to measure at least one parameter of the bio process environment. Also, the sensing sub-system includes a power source electrically coupled to the sensing unit and configured to transmit an electrical power to the sensing unit. Furthermore, the sensing sub-system includes a switch configured to electrically couple or decouple the sensing unit from the power source. In addition, the system includes a control sub-system including a first controller configured to determine at least one power control parameter based on a user-input data and a sensing sub-system data, and optimize consumption of the electrical power in the sensing sub-system, based on the power control parameter. ## Claims ### Claim 1 A system comprising: a sensing sub-system configured to be employed in a bioprocess environment, the sensing sub-system comprising: one or more sensing units configured to measure at least one parameter of the bioprocess environment or to detect a correct connection of two connector units; a power source electrically coupled to the sensing unit and configured to transmit an electrical power to the sensing unit; a switch configured to electrically couple or decouple the sensing unit from the power source; and a control sub-system comprising a first controller configured to: determine at least one power control parameter based on a user-input data and a sensing sub-system data; and optimize consumption of the electrical power in the sensing sub-system, based on the power control parameter. ### Claim 2 (depends on 1) The system of claim 1, wherein the control sub-system is disposed external to the sensing sub-system, and the control sub-system further comprises a first transceiver electrically coupled to the first controller and configured to transmit the at least one power control parameter to the sensing sub-system; and wherein the sensing sub-system further comprises: a second transceiver wirelessly coupled to the first transceiver and configured to receive the at least one power control parameter, and a second controller electrically coupled to the second transceiver and configured to control the consumption of the electrical power based on the at least one power control parameter. ### Claim 3 (depends on 2) The system of claim 2, wherein the second controller is electrically coupled to the switch and configured to: generate a switching signal based on the at least one power control parameter; and transmit the switching signal to the switch to control the electrical power transmission from the power source to the one or more sensing units. ### Claim 4 (depends on 3) The system of claim 3, wherein the switching signal comprises a plurality of pulses having a duty cycle corresponding to the at least one power control parameter. ### Claim 5 (depends on 1) The system of claim 1, wherein the second controller is electrically coupled to the second transceiver and configured to control a power level of a plurality of sensed signals transmitted from the one or more sensing units via the second transceiver, wherein the sensed signals represent the at least one measured parameter of the bioprocess environment. ### Claim 6 (depends on 1) The system of claim 1, wherein the at least one power control parameter comprises a transmission power value, a switching time value, a connection interval, a handshake power value, number of data bytes, and a parameter update rate associated with the sensing sub-system. ### Claim 7 (depends on 1) The system of claim 1, wherein the user-input data comprises data indicating at least one of time duration of operating the sensing sub-system, application of the sensing sub-system, and at least one desired parameter of a fluid in the bioprocess environment. ### Claim 8 (depends on 1) The system of claim 1, wherein the sensing sub-system data comprises data indicating at least one of type of the sensing sub-system and power consumption of the sensing sub-system. ### Claim 9 (depends on 1) The system of claim 1, wherein the sensing sub-system is a single-use device that is disposable after a cycle of bioprocess operation. ### Claim 10 (depends on 1) The system of claim 1, wherein the at least one measured parameter of the bioprocess environment comprises pressure of a fluid in the bioprocess environment, electrical conductivity of the fluid, dissolved gas level in the fluid, temperature of the fluid, glucose flow in the fluid, a potential of hydrogen (pH) level in the fluid, a cell viability in the fluid, a flow rate of the fluid, and a level of foam in the fluid. ### Claim 11 (depends on 2) The system of claim 2, wherein the first controller is configured to receive at least one of a power level in the power source and a transmission power value from the sensing sub-system; change the at least one power control parameter based on the at least one of the power level in the power source and the transmission power value; and transmit the at least one changed power control parameter to the second controller. ### Claim 12 (depends on 2) The system of claim 2, wherein the second controller is configured to control the consumption of the electrical power based on the at least one changed power control parameter. ### Claim 13 (depends on 1) The system of claim 1, wherein the sensing sub-system is coupled to a bioreactor comprising a flexible cell culture bag. ### Claim 14 A method comprising: measuring, by a sensing unit in a sensing sub-system configured to be employed in a bioprocess environment, at least one parameter of the bioprocess environment, or detecting by a pair of sensing units if two connector units have been correctly connected; determining, by a first controller in a control sub-system, at least one power control parameter based on a user-input data and a sensing sub-system data; and optimizing, by the first controller, consumption of the electrical power in the sensing sub-system based on the at least one power control parameter; ### Claim 15 (depends on 14) The method of claim 14, further comprising: wirelessly transmitting, by a first transceiver in the control sub-system, the at least one power control parameter to the sensing sub-system; receiving, by a second transceiver in the sensing sub-system, the at least one power control parameter from the first transceiver; and controlling, by a second controller in the sensing sub-system, the consumption of the electrical power based on the at least one power control parameter. ### Claim 16 (depends on 15) The method of claim 15, wherein controlling, by the second controller in the sensing sub-system, the consumption of the electrical power comprises: generating, by the second controller, a switching signal based on the at least one power control parameter; and transmitting, by the second controller, the switching signal to the switch to control the electrical power transmission from the power source to the one or more sensing units. ### Claim 17 (depends on 16) The method of claim 16, wherein the switching signal comprises a plurality of pulses having a duty cycle corresponding to the at least one power control parameter. ### Claim 18 (depends on 15) The method of claim 15, wherein controlling, by the second controller in the sensing sub-system, the consumption of the electrical power comprises controlling, by the second controller, a power level of a plurality of sensed signals transmitted from the one or more sensing units via the second transceiver, wherein the sensed signals represent the at least one parameter of the bioprocess environment. ### Claim 19 (depends on 14) The method of claim 14, wherein the power control parameter comprises a transmission power value, a switching time value, a connection interval, a handshake power value, number of data bytes, and a parameter update rate associated with the sensing sub-system. ### Claim 20 (depends on 14) The method of claim 14, wherein the user-input data comprises data indicating at least one of time duration of operating the sensing sub-system, application of the sensing sub-system, and at least one desired parameter of fluid in the bioprocess environment. ### Claim 21 (depends on 14) The method of claim 14, wherein the sensing sub-system is a single-use device that is disposable after a cycle of bioprocess operation. ### Claim 22 (depends on 14) The method of claim 14, wherein the at least one measured parameter of the bioprocess environment comprises pressure of a fluid in the bioprocess environment, electrical conductivity of the fluid, dissolved gas level in the fluid, temperature of the fluid, glucose flow in the fluid, a potential of hydrogen (pH) level in the fluid, a cell viability in the fluid, a flow rate of the fluid, and a level of foam in the fluid. ### Claim 23 (depends on 14) The method of claim 14, wherein the bioprocess environment comprises a bioreactor comprising a flexible cell culture bag. ### Claim 24 A system comprising: a plurality of wireless sensing sub-systems that are single-use and configured to be employed in a bioprocess environment, wherein each of the plurality of wireless sensing sub-systems comprises: a sensing unit configured to measure at least one parameter of the bioprocess environment; a power source electrically coupled to the sensing unit and configured to transmit an electrical power to the sensing unit; a switch configured to electrically couple or decouple the sensing unit from the power source; and a control sub-system wirelessly coupled to the plurality of wireless sensing sub-systems, wherein the control sub-system comprises a first controller configured to: determine at least one power control parameter based on a user-input data and a sensing sub-system data of a corresponding wireless sensing sub-system; and optimize consumption of the electrical power in the corresponding wireless sensing sub-system, based on the power control parameter.