# US 2020/0390102 A1 · Synergistic antimicrobial composition

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- Number: US 2020/0390102 A1
- Document ID: US20200390102A1
- Status: Published application
- Kind: A1
- Application number: 16/767,192
- Filed: 2018-12-17
- Published: 2020-12-17
- Earliest claimed: 2017-12-19
- Assignees: Ddp Specialty Electronic Materials US, LLC
- Applicants: Ddp Specialty Electronic Materials US, Inc.
- Inventors: Geert Van Der Kraan; Nora Eibergen; Nigel Watson; Imke Widera; Kenneth Wunch; James Donovan
- Web page: https://patentgrep.com/patent/US20200390102A1

## CPC

- A01N 57/20: containing acyclic or cycloaliphatic radicals
- A01N 35/02: containing aliphatically bound aldehyde or keto groups, or thio analogues thereof; Derivatives thereof, e.g. acetals
- A01N: PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF (preservation of food or foodstuff A23); BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES (preparations for medical, dental or toiletry purposes which kill or prevent the growth or proliferation of unwanted organisms A61K); PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS

## Abstract

A synergistic antimicrobial composition having two components. The first component is tetrakis(hydroxymethyl)phosphonium sulfate. The second component is glyoxal.

## Claims

### Claim 1

A synergistic antimicrobial composition comprising: (a) tetrakis(hydroxymethyl)phosphonium sulfate; and (b) glyoxal; wherein a weight ratio of tetrakis(hydroxymethyl)phosphonium sulfate to glyoxal is from 1:0.34 to 1:20.8.

### Claim 2 (depends on 1)

The synergistic antimicrobial composition of claim 1 in which the weight ratio of THPS to glyoxal is from 1:0.34 to 1:7.5.

### Claim 3

A method for inhibiting growth of Pseudomonas aeruginosa or Escherichia coli comprising adding to a medium which may contain at least one of Pseudomonas aeruginosa and Escherichia coli a combination of THPS and glyoxal in a range from 1:1.4 to 1: 20.8.

### Claim 4

A method for inhibiting growth of Thermus thermophilus comprising adding to a medium which may contain Thermus thermophilus a combination of THPS and glyoxal in a range from 1:0.34 to 1:1.