Method in a Chromatography System
AssigneeGE Healthcare Bio-Sciences AB
InventorsPetra Bangtsson, Erik Estrada, Karol Lacki, Helena Skoglar
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Abstract
There is provided a method and a corresponding system for determining binding capacities of a chromatography column. The method includes detecting a feed signal representative of the composition of a feed material provided to the inlet of the column. The method further includes detecting an effluent signal representative of the composition of the effluent from the column. The method further includes using the feed signal and the effluent signal to determine binding capacities of the column.
Claims25
A method for determining binding capacities of a chromatography column, comprising:
- detecting a feed signal representative of the composition of a feed material provided to the inlet of the column;
- detecting an effluent signal representative of the composition of the effluent from the column;
- and
- using the feed signal and the effluent signal to determine binding capacities of the column.
A chromatography system comprising at least one chromatography column, comprising:
- a first detector adapted to detect a feed signal being representative of the composition of a feed material provided to the inlet of the at least one column;
- a second detector adapted to detect an effluent signal being representative of the composition of the effluent from a first column of the system;
- and
- a determining unit connected to said detectors and adapted to determine binding capacities of the first column based on said feed signal and said effluent signal.
Dependencies are inferred from the claim text.