Programmable gene expression system
AssigneeHisashi TADAKUMA
InventorsHisashi TADAKUMA, Takeya MASUBUCHI, Yoshie HARADA
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Abstract
An object to the present invention is to provide a device for genetic circuits that is under extremely reduced restrictions on the materials of a sensor sensing the environment, capable of performing controlled gene expression with sufficiently suppressed crosstalk, and a genetic circuit containing the device. The present invention relates to a device for a genetic circuit, containing an open-close mechanism constituted of a catalyst, a target gene, and a shape change element, wherein the catalyst induces an expression of the target gene by contacting the target gene, and the like.
Claims19
A device for a gene circuit, comprising an open-close mechanism constituted of a catalyst, a target gene, and a shape change element, wherein
- the catalyst induces an expression of the target gene by contacting the target gene,
- the shape change element has a first site and a second site, and has a structure in which a distance between the first site and the second site changes by an action of an activation source, and
- the open-close mechanism has the shape change element as a movable part, and is configured to perform an open-close motion in which the target gene and the catalyst relatively approach and contact with each other or relatively leave the contact state in response to a change in the distance between the first site and the second site in the shape change element.
Dependencies are inferred from the claim text.