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US 2020/0370018 A1Published application
Culture medium composition for maturating cardiomyocytes derived from pluripotent mammalian stem cells
AssigneeNcardia B.V.
InventorStefan Robbert Braam
Life of this patent
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Abstract
The current disclosure relates to a culture medium, different methods to generate adult-like cardiomyocytes from pluripotent embryonic stem cells (ESC) and/or (induced) pluripotent stem cells (iPSC) using the medium, in particular from stem cells that differentiated into (foetal) cardiomyocytes, and to kits comprising the medium, or the medium together with differentiated (foetal) cardiomyocytes derived from pluripotent embryonic stem cells (ESC) and/or (induced) pluripotent stem cells (iPSC).
Claims20
An aqueous culture medium composition, wherein said culture medium composition is serum-free and comprises:
- a thyroid hormone-like compound;
- a lipid mixture;
- and
- a carnitine compound.
1 more element
Dependencies are inferred from the claim text.