Complex, Preparation Methods and Application Thereof
AssigneeBioright Worldwide Company Limited
InventorsChung Hong Cheung, Jun Wang
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Abstract
The invention is directed to a complex, including: a porous composite carrier including: a porous organic foam material containing open pores, each pore comprising a wall defining the pore; and a crosslinked product having aldehyde groups and immobilized on the surface of the walls of one or more pores of the porous organic foam materials, and a protein, polypeptide, or oligopeptide immobilized onto the porous composite carrier through a reaction between an amino group of the protein, polypeptide or oligopeptide and an aldehyde group of the composite carrier. The immobilized product has high specific surface area and high specific activity. The immobilization is simple and in low cost, and is suitable for industrial application.
Claims20
A complex, comprising:
- a porous composite carrier comprising:
- a porous organic foam material containing open pores, each pore comprising a wall defining the pore;
- and
- a crosslinked product having aldehyde groups and immobilized on the surface of the walls of one or more pores of the porous organic foam materials, and
- a protein, polypeptide, or oligopeptide immobilized onto the porous composite carrier through a reaction between an amino group of the protein, polypeptide or oligopeptide and an aldehyde group of the composite carrier.
A method for preparing a complex of a porous composite carrier and a protein, polypeptide, or oligopeptide immobilized onto the porous composite carrier, comprising the following steps:
- a) providing a porous composite carrier comprising:
- a porous organic foam material containing open pores, each pore comprising a wall defining the pore;
- and
- a crosslinked product having aldehyde groups and immobilized on the surface of the walls of one or more pores of the porous organic foam materials;
- b) immobilizing the protein, polypeptide or oligopeptide onto the porous composite carrier through a reaction between an amino group of the protein, polypeptide or oligopeptide and an aldehyde group of the porous composite carrier.
Dependencies are inferred from the claim text.