Aligned fiber and method of use thereof
AssigneeLifeNet Health
InventorsMichael Francis, Roy Ogle
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Abstract
A scaffold comprising an aligned fiber. Further, a scaffold comprising one or more electrospun fibers wherein a fast Fourier transform (FFT) analysis result of the fibers have adjacent major peaks with about 180° apart from each other. Also, methods for promoting differentiation of stem cells into osteoblasts, chondrocytes, ligament or tendon, the method comprising culturing the cells on the scaffold or aligned fiber in conditions suitable for the cell differentiation.
Claims25
A scaffold comprising one or more fibers comprising collagen, wherein the fibers are anisotropic based on a fast Fourier transform (FFT) analysis, and wherein the anisotropic fibers are crosslinked and comprise type I collagen in its triple helical structure.
Dependencies are inferred from the claim text.