Reduced and oxidized polysaccharides and methods of use thereof
AssigneePresident and Fellows of Harvard College
InventorsDavid J. Mooney, Alexander Stafford, Rajiv Desai, Kathleen Martinick
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Abstract
The present invention is directed to reduced and highly oxidized polysaccharides, such as alginates, that are useful for encapsulating therapeutic or diagnostic agents, or lipid based nanoparticles, e.g., liposomes or virosomes, encapsulating therapeutic or diagnostic agents, prior to their delivery into a subject, as well as methods for making and using them.
Claims26
A composition comprising a highly oxidized polysaccharide and a cross-linking agent attached to the highly oxidized polysaccharide.
A hydrogel comprising a plurality of highly oxidized polysaccharides cross-linked to each other, wherein said hydrogel comprises a mesh size of 10 nm or less.
Dependencies are inferred from the claim text.