Loading patent…
AssigneePfizer Inc.
InventorsAnnaliesa Sybil Anderson, Leena Shriram Bagle, Amardeep Singh Bhupender Bhalla, Miguel Angel Garcia, Lei Hu, Lakshmi Khandke, Avvari Krishna Prasad, Cindy Xudong Yang
Estimating the term…
The invention relates to immunogenic compositions comprising a capsular polysaccharide (CP) from Streptococcus agalactiae, commonly referred to as group B streptococcus (GBS), conjugated to a carrier protein, and optionally including an aluminum-based adjuvant. The invention further relates to methods for inducing an immune response in subjects against GBS and/or for reducing or preventing invasive GBS disease in subjects using the compositions disclosed herein. The resulting antibodies can be used to treat or prevent GBS infection via passive immunotherapy.
A method of inducing an immune response against group B streptococcus in a subject comprising administering to the subject an effective amount of an immunogenic composition comprising polysaccharide-carrier protein conjugates, wherein:
The method of 6, wherein the female is in her second half of pregnancy.
A method of preventing or reducing a disease or condition associated with group B streptococcus in a subject comprising administering to the subject an effective amount of an immunogenic composition comprising polysaccharide-carrier protein conjugates, wherein:
The method of 15, wherein the female is in her second half of pregnancy.
Dependencies are inferred from the claim text.