Cell population including adhesive stem cells, production method therefor and pharmaceutical composition
AssigneeKaneka Corporation
InventorsNobuyoshi UMEDA, Keita INO, Chiho KOBAYASHI
Life of this patent
Estimating the term…
Abstract
An object of the present invention is to provide a cell population comprising safe adherent stem cells maintaining a normal karyotype and a method for producing the cell population, and a pharmaceutical composition comprising the cell population. According to the present invention, a production method of a cell population comprising adherent stem cells, comprising obtaining a cell population in which the proportion of KCNAB1-positive adherent stem cells in the cell population is 85% or more, is provided.
Claims17
A method for producing a cell population comprising adherent stem cells, comprising obtaining a cell population having 85% or more KCNAB1-positive adherent stem cells.
A cell population comprising adherent stein cells, wherein the cell population has 85% or more KCNAB1-positive adherent stem cells.
The cell population according to claim wherein a relative expression level of RARRES2 gene to an expression level of SDHA gene is 0.4 or less.
The cell population according to claim wherein the adherent stem cells are derived from a fetal appendage.
A method for evaluating a cell population comprising adherent stem cells, comprising measuring a proportion of KCNAB1-positive adherent stem cells, and using the proportion of KCNAB1-positive adherent stem cells in the cell population being 85% or more as an index.
Dependencies are inferred from the claim text.