Platform for generating safe cell therapeutics
AssigneeThe Regents of the University of California
InventorsRichard Klemke, Huawei Wang
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Abstract
Provided herein are cytoplasts, compositions comprising cytoplasts, methods of using cytoplasts, and methods of treating a subject, such as providing benefits to a healthy or unhealthy subject, or treating or diagnosing a disease or condition in a subject. In some embodiments, methods of treating a subject include: administering to the subject a therapeutically effective amount of a composition comprising a cytoplast. Also, provided herein are compositions (e.g., pharmaceutical compositions) that include a cytoplast. Also, provided herein are kits comprising instructions for using the compositions or methods.
Claims20
A method comprising:
- administering to a subject a therapeutically effective amount of a composition comprising a first cytoplast expressing or containing at least one therapeutic agent.
A cytoplast comprising at least one therapeutic agent.
A method of making a cytoplast, the method comprising:
- introducing into a cell a therapeutic agent;
- and
- enucleating the cell.
Dependencies are inferred from the claim text.