Tlr7 agonist maleate salt, crystalline forms c, d and e thereof, preparation methods and uses of maleate salt and crystalline forms
AssigneeChia Tai Tianqing Pharmaceutical Group Co., Ltd.
InventorsZhaozhong DING, Fei SUN, Yinghu HU, Yilong ZHOU, Zheng WANG, Ling YANG
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Abstract
The present invention relates to a maleate salt of a compound represented by formula I, a method for preparing the salt, a pharmaceutical composition containing the salt, and the use of the salt. The present invention also relates to crystalline forms C, D and E of the maleate salt of the compound represented by formula I, methods for preparing the crystalline forms, crystalline compositions and pharmaceutical compositions containing the crystalline forms, and uses thereof.
Claims20
-10. (canceled)
A crystal form C of a maleate of a compound of formula I, wherein the crystal form C has diffraction peaks at 2θ=5.6°±0.2°, 7.6°±0.2°, 9.9°±0.2°, 17.8°±0.2°, 19.8°±0.2°, 22.8°±0.2°, 24.2°±0.2°, 25.0°±0.2°, 26.3°±0.2° in X-ray diffraction pattern
A crystal form D of a maleate of a compound of formula I, wherein the crystal form D has diffraction peaks at 2θ=5.1°±0.2°, 9.5°±0.2°, 11.2°±0.2°, 17.6°±0.2°, 20.2°±0.2°, 20.7°±0.2°, 23.0°±0.2°, 23.7°±0.2° in X-ray diffraction pattern
A crystal form E of a maleate of a compound of formula I, wherein the crystal form E has diffraction peaks at 2θ=4.9°±0.2°, 5.3°±0.2°, 6.7°±0.2°, 9.0°±0.2°, 10.8°±0.2°, 16.5°±0.2°, 19.3°±0.2° in X-ray powder diffraction pattern
Dependencies are inferred from the claim text.