Methods and combination therapy to treat cancer
AssigneeArray BioPharma Inc.
InventorsPatrice A. LEE, David CHANTRY, Shannon L. WINSKI
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Abstract
This invention relates to a method of treating cancer by administering to a patient in need thereof, over a period of time, therapeutic agents that consist essentially of a MEK inhibitor which is binimetinib or a pharmaceutically acceptable salt thereof, and a PD-1 binding antagonist, to a patient in need thereof.
Claims33
A method for treating cancer consisting essentially of administering to a patient in need thereof, over a period of time, therapeutic agents that consist essentially of an amount of a PD-1 binding antagonist and an amount of a MEK inhibitor which is binimetinib or a pharmaceutically acceptable salt thereof, wherein the amounts together are effective in treating cancer.
A combination therapy method consisting essentially of administering, over a period of time, to a patient in need thereof, therapeutic agents that consist essentially of therapeutically effective amounts, independently or in combination, of:
- a MEK inhibitor, which is binimetinib or a pharmaceutically acceptable salt thereof;
- and
- a PD-1 binding antagonist.
Dependencies are inferred from the claim text.