Dry Powder Compositions for Intranasal Delivery
AssigneeFormulex Pharma Innovations Ltd.
InventorGalia Temtsin-Krayz
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AssigneeFormulex Pharma Innovations Ltd.
InventorGalia Temtsin-Krayz
Estimating the term…
The present application relates to a pharmaceutical composition in a form of dry powder for intranasal administration, comprising solid particles of at least one active agent and solid particles of a diluent, said pharmaceutical composition being substantially free of excipients other than the solid diluent, wherein said pharmaceutical composition having at least 90% of the particles of said at least one active agent with a mean particle size of 10-30 microns and less than 10% of the particles of said at least one active agent with a mean particle size equal to or below 5 microns. The particles of said diluent have a mean particle size of 30-200 microns. The present application also relates to an apparatus and modified spray drying method for preparation of the pharmaceutical composition of the present invention in the dry powder form.
A pharmaceutical composition in a form of dry powder for intranasal administration to a patient in need thereof, comprising solid particles of at least one active agent and solid particles of a diluent, wherein said pharmaceutical composition is free of excipients other than the solid diluent, and has at least 90% of the particles of said at least one active agent with a mean particle size ranging from 10 microns to 30 microns, and less than 10% of the particles of said at least one active agent with a mean particle size equal to or below 5 microns.
Dependencies are inferred from the claim text.