Liquid depot for non-invasive sustained delivery of agents to the eye
AssigneeIdrop , Inc.
InventorsVernon G. Wong, Glenn T. Huang
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Abstract
The present embodiments provide compositions, methods, and kits for the treatment or prevention of ocular conditions or maladies via non-invasive liquid depots. In at least one embodiment, the liquid depot is capable of sustained-release delivery of at least one pharmaceutical agent to the eye for days or weeks.
Claims23
A liquid depot for sustained release of an active agent in the eye, the liquid depot comprising:
- a tocopherol;
- an ocular film-forming excipient;
- and an active agent;
- wherein the liquid depot has a viscosity of about 850 cP to about 1100 cP, inclusive.
A method of treating a malady of the eye in a subject in need thereof, comprising topically administering to the eye of the subject a liquid depot comprising (a) at least one active agent;
- and (b) a mixture of mixture of tocopheryl acetate:medium-chain triglycerides at a weight ratio of about 90:10 to about 60:40.
21-26. (canceled)
A liquid depot comprising:
- a tocopherol;
- an ocular film-forming excipient;
- and, optionally, an active agent;
- wherein the liquid depot has a viscosity of about 850 cP to about 1100 cP, inclusive.
28-33. (canceled)
Dependencies are inferred from the claim text.