Abuse deterrent immediate release formulations comprising non-cellulose polysaccharides
AssigneeSpecGX LLC
InventorsAlex Micka, Kai Feng, Tsz Chung Lai, Jonathan Gaik
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Abstract
The present disclosure provides pharmaceutical compositions that provide immediate release of active ingredients and have abuse deterrent properties. In particular, the pharmaceutical compositions comprise at least one pharmaceutically active ingredient, at least one non-cellulose polysaccharide, at least one hydrophilic gelling polymer, and an effervescent system.
Claims16
A pharmaceutical composition comprising a mixture of an opioid, about 10% w/w to about 25% w/w of at least one natural gum comprising glucomannan, about 25% w/w to about 35% w/w of a combination of hydrophilic gelling polymers comprising (i) at least one cellulose ether, (ii) a polyethylene oxide having an average molecular weight of about 100,000, and (iii) a polyethylene oxide having an average molecular weight of about 4,000,000, and about 40% w/w to about 50% w/w of an effervescent system, wherein the pharmaceutical composition provides immediate release of the opioid and has abuse deterrent properties.
Dependencies are inferred from the claim text.