Geometrically-accommodating heart valve replacement device
AssigneesChildren's Medical Center Corporation, President and Fellows of Harvard College, Massachusetts Institute of Technology
InventorsSophie-Charlotte Hofferberth, Pedro J. del Nido, Elazer R. Edelman, Peter E. Hammer, Christopher Payne
Life of this patent
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Abstract
A replacement heart valve device is disclosed. In some embodiments, the device includes a frame coupled to one or more leaflets that are moveable between open and closed configurations. In some embodiments, the frame comprises at least two frame sections that join at a pair of commissural posts. In some embodiments, the device may be geometrically accommodating to adapt to different vasculature shapes and sizes and/or to be able to change size while implanted within a growing patient.
Claims31
A valve replacement device, comprising:
- a valve frame defining an opening for passage of fluid, the opening having a diameter along a largest dimension of the opening, the valve frame being expandable to permit an increase in the diameter of the opening from 5 mm to 50 mm;
- and
- a first leaflet coupled to the valve frame, the first leaflet having an open configuration in which the opening is exposed, and a closed configuration in which the first leaflet at least partially covers the opening,
- wherein the valve frame is expandable to permit an increase in the diameter of the opening, and wherein the first leaflet is moveable between the open and closed configurations as the diameter of the opening expands from 5 mm to 50 mm,
- wherein the first leaflet maintains a constant surface area with expansion or contraction of the valve frame.
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A valve replacement device, comprising:
- a valve frame defining an opening for passage of fluid, the opening having a diameter along a largest dimension of the opening, the valve frame being expandable to permit an increase in the diameter of the opening from 5 mm to 50 mm;
- and
- a first leaflet coupled to the valve frame, the first leaflet having an open configuration in which the opening is exposed, and a closed configuration in which the first leaflet at least partially covers the opening,
- wherein the valve frame is expandable to permit an increase in the diameter of the opening, and wherein the first leaflet is moveable between the open and closed configurations as the diameter of the opening expands from 5 mm to 50 mm,
- wherein the valve frame comprises first and second frame sections connected by a pair of commissures, and
- wherein the first frame section forms a U-shape having two arms extending away from an intermediate section, the intermediate section forming a base of the first frame section.
32-35. (canceled)
A valve replacement device comprising:
- a valve frame defining an opening for passage of fluid, the valve frame having a diameter along a largest dimension of the opening, the valve frame having a height in a direction perpendicular to the diameter, the valve frame being expandable to increase the diameter in an operational configuration and contractible to decrease the diameter in a contracted configuration and having a height to diameter ratio ranging from 0.5:1 to 2.5:1 in the operational configuration;
- and
- a first leaflet coupled to the frame,
- wherein as the frame expands, the height decreases as the diameter increases.
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Dependencies are inferred from the claim text.