A microorganism curing anti-seepage device based on capsule transmission and control, the device comprising a stock bin (1) which comprises a mixing bin (9) and an oil storage bin (10) separated from the mixing bin (9), wherein a feed pipe (21 communicated with the mixing bin (9) is provided on the stock bin (1), microbial capsules and water enter the mixing bin (9) through the feed pipe (2), an oil injection pipe (7) communicated with the oil storage bin (10) is provided on the stock bin (1), a central shaft (8) is rotatably located within the mixing bin (9), a stirring component is provided on the central shaft (8), a delivery pipe (21) is provided at a bottom portion of the mixing bin (9), an oil conduit (14) communicated with the delivery pipe (21) is provided at a bottom portion of the oil storage bin (10), a jet pipe (15) is provided at a junction of the oil conduit (14) and the delivery pipe (21), an adjustment component is provided on the delivery pipe (21) for controlling opening or closing between the delivery pipe (21) and the jet pipe (15).