Clear Cell Renal Cell Carcinoma Biomarkers
AssigneesAgency for Science, Technology and Research, Singapore Health Services Pte Ltd
InventorsXiaosai Yao, Patrick Tan, Bin Tean Teh, Jing Tan, Huilin Shao, Joanna Koh
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Abstract
Disclosed herein is a clear cell renal cell carcinoma (ccRCC) biomarker set. Also disclosed herein is a detection system using the biomarker set disclosed herein, methods of determining whether a subject has or shows recurrence of clear cell renal cell carcinoma, method of determining whether a renal mass sample is benign or malignant, method of detecting response of a subject to systemic treatment, and a kit for carrying out the same.
Claims20
A clear cell renal cell carcinoma (ccRCC) biomarker set, wherein the biomarker set comprises at least two biomarkers selected from the group consisting of ZNF395, SMPDL3A, SLC28A1, SLC6A3, VEGFA, EGLN3, wherein one of the at least two biomarkers is SMPDL3A or SLC28A1;
- wherein the biomarkers are proteins, or nucleic acids encoding the same, or variants thereof.
Dependencies are inferred from the claim text.