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AssigneeSelux Diagnostics, Inc.
InventorsKristin Baker, Kelly Flentie, Aleksandar Vacic, Eric Stern, Ali Ersen, Benjamin R. Spears, Matthew Briscoe
Estimating the term…
Continuous monitoring of blood cultures using pH- (or CO2—) based detection platforms is the current clinical gold standard. Despite the ubiquity of these systems in state-of-the-art clinical microbiology laboratories, they offer slow times-to-result (TTR) because microorganism detection typically requires >109 colony forming units (CFU) to be present whereas only 1-1000 CFU are typically present in septic patient blood samples. These TTRs are further lengthened for samples collected from spoke sites in consolidated hub-and-spoke laboratory models, an increasingly common model for integrated hospital networks and reference laboratories, because sample transport time, typically >4 hours, is lost. Here we introduce new methods that allow microorganisms to be detected at <105 CFU and that enable sample incubation during courier transport from spoke collection sites to the central laboratory hub.
A method of interrogating a blood sample for microorganisms, comprising:
A method of interrogating a blood sample for microorganisms, comprising:
A method of detecting microbial growth in a blood sample, comprising the steps of:
Dependencies are inferred from the claim text.