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US 2020/0347367 A1Published application
Activation of APC in Immunotherapy
AssigneeInnovative Cellular Therapeutics Holdings, Ltd.
InventorsChengfei Pu, Lei Xiao, He Sun, Xiaogang Shen, Cheng Lu
Life of this patent
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Abstract
Embodiments relate to compositions and methods for treating solid tumors. For example, the compositions comprise modified cells comprising an isolated polynucleotide comprising a polynucleotide encoding a nuclear factor of activated T cells (NFAT) promoter operatively associated with a polynucleotide encoding FLT3L.
Claims20
An isolated polynucleotide comprising a polynucleotide encoding a nuclear factor of activated T cells (NFAT) promoter operatively linked to a polynucleotide encoding Fms-related tyrosine kinase 3 ligand (FLT3L).
Dependencies are inferred from the claim text.