Composition and method for increasing production of bacteriophage using reactive oxygen species
AssigneeHankuk University of Foreign Studies Research & Business Foundation
InventorsHeejoon MYUNG, Yunyeol JO
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Abstract
Provided is a method and composition using ROS to increase the production of bacteriophage. According to the subject matter, a production amount of bacteriophage is increased several times in the presence of the sublethal concentration of ROS for host bacteria. Therefore, the method and composition of the subject matter can be useful for producing bacteriophage, which is used as an alternative to antibiotics that cause a serious resistance problem.
Claims16
A composition for increasing the production of a bacteriophage comprising ROS (Reactive Oxygen Species), wherein the ROS is comprised at the sublethal concentration for a host bacterium infected by the bacteriophage.
A method of increasing the production of bacteriophage comprising incubating a host bacterium and a bacteriophage that specifically infect the host bacterium in the presence of sublethal concentration of ROS for the host bacteria, whereby the production of bacteriophage is increased.
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Dependencies are inferred from the claim text.