US 2020/0347347 A1 · COMPOSITIONS AND METHODS FOR IMPROVED GAMETE VIABILITY AND FUNCTION

Abstract

The present specification provides for a media composition that provides enhanced viability and activity to sperm cells.

Dependent claims

A media formulation comprising a basic salt media and at least one additive,

wherein the basic salt media comprises at least one component selected from the group consisting of sodium chloride (NaCl), potassium chloride (KCl), calcium chloride dihydrate (CaCl2.2H2O), magnesium chloride, hexahydrate (MgCl2.6H2O), sodium bicarbonate (NaHCO3), sodium phosphate monobasic dehydrate (NaH2PO42H2O), potassium dihydrogen phosphate (KH2PO4), fructose, sorbitol, bovine serum albumin (BSA), citric acid, and combinations thereof, and
wherein the at least one additive comprises phosphatidylserine (PS) and an NSAID.

Dependencies are inferred from the claim text.

Facts

Application

16/760,398Filed 30 Oct 2018

Priority

30 Oct 2017

Published

5 Nov 2020

Term ends

Not estimatedThe source records don’t support an estimate.

A01N 1/122
Chemical aspects of preservation: preservation or perfusion media
C12N 5/0018
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor: culture media…
A01N 1/126
Preservation or perfusion media: physiologically active agents, e.g. antioxidants or nutrients
A01N 1/162
Physical preservation processes: temperature processes, e.g. following predefined temperature changes over time

The present specification provides for a media composition that provides enhanced viability and activity to sperm cells.

Dependent claims

A media formulation comprising a basic salt media and at least one additive,

wherein the basic salt media comprises at least one component selected from the group consisting of sodium chloride (NaCl), potassium chloride (KCl), calcium chloride dihydrate (CaCl2.2H2O), magnesium chloride, hexahydrate (MgCl2.6H2O), sodium bicarbonate (NaHCO3), sodium phosphate monobasic dehydrate (NaH2PO42H2O), potassium dihydrogen phosphate (KH2PO4), fructose, sorbitol, bovine serum albumin (BSA), citric acid, and combinations thereof, and
wherein the at least one additive comprises phosphatidylserine (PS) and an NSAID.

Dependencies are inferred from the claim text.