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AssigneesQueen's University at Kingston, Kingston Health Sciences Centre, Emory University, Georgia Tech Research Corporation
InventorsPhilip ZAKAS, David LILLICRAP, Christopher DOERING, Eric GAUCHER, Caelan RADFORD, Harold Trent SPENCER
Estimating the term…
A recombinant von Willebrand Factor (VWF) protein comprising one or more mutations and uses thereof are described. A recombinant protein complex comprising a von Willebrand factor sequence and one artificial Factor VIII sequence is described. A recombinant protein complex comprising a Factor VIII sequence and one artificial von Willebrand sequence is described. A recombinant protein complex is described that includes one artificial von Willebrand factor sequence and one artificial Factor VIII sequence. Also described are nucleic acid sequences and a vector encoding a VWF sequence and a pharmaceutical composition for inducing blood clotting that includes a VWF protein.
A recombinant von Willebrand Factor (VWF) protein comprising one or more mutations wherein one or more amino acids are substituted compared to SEQ ID NO:
A pharmaceutical composition comprising a nucleotide of SEQ ID Nos. 1 to 5, or a combination thereof.
A composition comprising at least one recombinant protein, wherein the composition comprises:
A vector comprising a promotor nucleic acid sequence in operable combination with:
Dependencies are inferred from the claim text.