Conjugatable desmoglein 2 (dsg2) binding proteins and uses therefor

Abstract

The disclosure provides polypeptide compositions that open a tumor tight junction, comprising an adenovirus fiber polypeptide shaft domain motif; a sequence that opens a tumor tight junction; a multimerization domain; and a conjugatable moiety. In another aspect, the multimerization domain comprises a conjugatable moiety.

Dependencies are inferred from the claim text.