Drug Delivery Devices and Methods for Use with a Urinary Catheter
AssigneeTARIS Biomedical LLC
InventorsJoseph Kalt, Heejin Lee
Life of this patent
Estimating the term…
Abstract
Drug delivery devices (200) and methods of their use are provided. In one embodiment, a drug delivery device (200) for use with a urinary catheter (100) includes a drug reservoir configured to be disposed outside of a patients body, and a flexible elongate body (220) attached to the drug reservoir (230) and configured to traverse the patients urethra to reach the bladder. The drug reservoir (230) includes a drug chamber (234) containing a drug therein, a fluid chamber (236) containing a fluid therein, and an osmotic barrier (238) separating the drug chamber (234) and the fluid chamber (236). The body includes a drug delivery lumen (222) extending therethrough and in fluid communication with the drug chamber (234).
Claims48
A drug delivery device for use with a urinary catheter, the drug delivery device comprising:
- a drug reservoir configured to be disposed outside of a patient's body, the drug reservoir comprising:
- a drug chamber containing a drug therein;
- a fluid chamber containing a fluid therein;
- and
- an osmotic barrier separating the drug chamber and the fluid chamber;
- and
- a flexible elongate body attached to the drug reservoir and configured to traverse the patient's urethra to reach the bladder, the body comprising a drug delivery lumen extending therethrough and in fluid communication with the drug chamber.
A urinary catheter and drug delivery system comprising:
- a urinary catheter configured to allow urine to drain from a patient's bladder, the urinary catheter comprising a flexible elongate catheter body configured to traverse the patient's urethra to reach the bladder, the catheter body comprising a drainage lumen extending therethrough;
- and
- a drug delivery device configured for use with the urinary catheter, the drug delivery device comprising:
- a drug reservoir configured to be disposed outside of the patient's body, the drug reservoir comprising:
- a drug chamber containing a drug therein;
- a fluid chamber containing a fluid therein;
- and
- an osmotic barrier separating the drug chamber and the fluid chamber;
- and
- a flexible elongate device body attached to the drug reservoir and configured to traverse the patient's urethra to reach the bladder, the device body comprising a drug delivery lumen extending therethrough and in fluid communication with the drug chamber.
A method of administering a drug to a patient in need thereof, the method comprising:
- inserting distal end portions of a drug delivery device and a urinary catheter through the patient's urethra and positioning the distal end portions within the bladder, while maintaining proximal end portions of the drug delivery device and the urinary catheter positioned outside of the patient's body;
- allowing urine to drain from the bladder through the urinary catheter;
- and
- delivering a drug, via osmotic pressure, from the proximal end portion of the drug delivery device into the bladder.
44-61. (canceled)
A urinary catheter and drug delivery system comprising:
- a urinary catheter configured to allow urine to drain from a patient's bladder, the urinary catheter comprising a flexible elongate catheter body configured to traverse the patient's urethra to reach the bladder, the catheter body comprising a drainage lumen extending therethrough from a distal opening to proximal opening defined in the catheter body;
- and
- a drug delivery device attached to the urinary catheter, the drug delivery device comprising a drug reservoir positioned near the distal opening of the drainage lumen and configured to be disposed within the patient's bladder, the drug reservoir comprising a drug chamber containing a drug therein.
63-84. (canceled)
A method of administering a drug to a patient in need thereof, the method comprising:
- inserting a drug delivery device and a distal end portion of a urinary catheter through the patient's urethra and positioning the drug delivery device and the distal end portion of the urinary catheter within the bladder, wherein the urinary catheter comprises a flexible elongate catheter body comprising a drainage lumen extending therethrough from a distal opening to proximal opening defined in the catheter body, and wherein the drug delivery device comprises a drug reservoir positioned near the distal opening of the drainage lumen and comprising a drug chamber containing a drug therein;
- allowing urine to drain from the bladder through the drainage lumen;
- and
- delivering the drug from the drug chamber into the bladder.
86-98. (canceled)
Dependencies are inferred from the claim text.