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US 2020/0345922 A1Published application
Apparatus for extracorporeal treatment of blood
AssigneeGambro Lundia AB
InventorDominique POUCHOULIN
Life of this patent
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Abstract
An apparatus for extracorporeal treatment of blood comprising a filtration unit, a blood withdrawal line, a blood return line, an effluent fluid line, a pre and/or post-dilution fluid line connected to the blood withdrawal line, and a dialysis fluid line. Pumps act on the fluid lines for regulating the flow of fluid. A control unit is configured to set initial values to one or more fluid flow rates through the above lines and to periodically execute a flow rate update procedure in order to deliver a set dose (Dset) in a reference time interval.
Claims20
An apparatus for extracorporeal treatment of blood comprising:
- a filtration unit having a primary chamber and a secondary chamber separated by a semi-permeable membrane;
- a blood withdrawal line connected to an inlet of the primary chamber;
- a blood return line connected to an outlet of the primary chamber, said blood withdrawal line and said blood return line being configured to be connected to a patient cardiovascular system;
- a blood pump configured for controlling a flow of blood through the blood withdrawal line;
- an effluent fluid line connected to an outlet of the secondary chamber;
- at least two fluid lines comprising:
- a pre-blood pump infusion line connected to the blood withdrawal line in a region of the blood withdrawal line that is positioned upstream the blood pump, and
- at least one of (i) a pre-dilution fluid line connected to the blood withdrawal line, and (ii) a post-dilution fluid line connected to the blood return line, and (iii) a dialysis fluid line connected to the inlet of the secondary chamber;
- one or more pumps and/or valves for regulating the flow of fluid through the at least two fluid lines;
- and
- a control unit configured to:
- calculate or receive initial set values of two or more fluid flow rates selected from the group including a fluid flow rate (Qeff) through the effluent line, a fluid flow rate (Qrep) through the pre-dilution fluid line or the post-dilution fluid line, a fluid flow rate (Qpbp) through the pre-blood pump infusion line, a fluid flow rate (Qdial) through the dialysis liquid fluid line, and a fluid removal rate (Qpfr) from the patient,
- calculate or receive at least a prescribed dose (Dset), said prescribed dose being a target mean value of one or more flow rates to be delivered across an entire patient treatment, and
- execute a flow rate update procedure comprising calculating updated set values for one or more of said fluid flow rates based on said prescribed dose (Dset) in order to deliver the prescribed dose (Dset) during a reference time interval, wherein the step of calculating the updated set values comprises maintaining the initial set value of the pre-blood pump infusion flow rate (Qpbp) at its initial set value.
11 more elements
An apparatus for extracorporeal treatment of blood comprising:
- a filtration unit having a primary chamber and a secondary chamber separated by a semi-permeable membrane;
- a blood withdrawal line connected to an inlet of the primary chamber;
- a blood return line connected to an outlet of the primary chamber, said blood withdrawal line and said blood return line being configured to be connected to a patient cardiovascular system;
- a blood pump configured for controlling a flow of blood through the blood withdrawal line;
- an effluent fluid line connected to an outlet of the secondary chamber;
- at least two fluid lines comprising:
- a pre-blood pump infusion line connected to the blood withdrawal line in a region of the blood withdrawal line that is positioned upstream the blood pump, and
- at least one of (i) a pre-dilution fluid line connected to the blood withdrawal line, (ii) a post-dilution fluid line connected to the blood return line, and (iii) a dialysis fluid line connected to the inlet of the secondary chamber;
- one or more pumps and/or valves for regulating the flow of fluid through the at least two fluid lines;
- a user interface;
- and
- a control unit connected to the user interface and configured to:
- calculate or receive set values of two or more fluid flow rates selected from the group including:
- a fluid flow rate (Qset) through the effluent line, a fluid flow rate (Qrep) through the pre-dilution fluid line or the post-dilution fluid line, a fluid flow rate (Qpbp) through the pre-blood pump infusion line, a fluid flow rate (Qdial) through the dialysis liquid fluid line, and a fluid removal rate (Qpfr) from the patient,
- display on the user interface an indicium prompting a user to select whether to enter in a dose control mode,
- responsive to detecting that the user selected to enter in the dose control mode:
- calculate a prescribed dose (Dset) based on initial set values of the two or more fluid flow rates or display an indicium prompting a user to enter the prescribed dose (Dset), wherein the prescribed dose is a target mean value of one or more flow rates to be delivered across an entire patient treatment,
- execute a flow rate update procedure comprising calculating updated set values of the two or more fluid flow rates based on the prescribed dose (Dset) in order to deliver the prescribed dose during a reference time interval, and
- control said one or more pumps and/or valves for regulating the flow of fluid based on the updated set values,
- responsive to detecting that the user selected to not enter in the dose control mode:
- display on the user interface an indicium prompting a user to enter via the user interface set values of two or more of said fluid flow rates, and
- control said one or more pumps and/or valves for regulating the flow of fluid based on said set values entered via the user interface.
19 more elements
An apparatus for extracorporeal treatment of blood comprising:
- a filtration unit having a primary chamber and a secondary chamber separated by a semi-permeable membrane;
- a blood withdrawal line connected to an inlet of the primary chamber;
- a blood return line connected to an outlet of the primary chamber, said blood withdrawal line and said blood return line being configured to be connected to a patient cardiovascular system;
- a blood pump configured for controlling a flow of blood through the said blood withdrawal line;
- an effluent fluid line connected to an outlet of the secondary chamber;
- at least two fluid lines comprising:
- a pre-blood pump infusion line connected to the blood withdrawal line in a region of the blood withdrawal line that is positioned upstream the blood pump, and
- at least one of (i) a pre-dilution fluid line connected to the blood withdrawal line, (ii) a post-dilution fluid line connected to the blood return line, and (iii) a dialysis fluid line connected to the inlet of the secondary chamber;
- one or more pumps and/or valves for regulating the flow of fluid through the at least two fluid lines;
- a user interface;
- and
- a control unit connected to the user interface and configured to:
- calculate or receive initial set values of two or more fluid flow rates selected from the group including:
- a fluid flow rate (Qeff) through the effluent line, a fluid flow rate (Qrep) through the pre-dilution fluid line or the post-dilution fluid line, a fluid flow rate (Qpbp) through the pre-blood pump infusion line, a fluid flow rate (Qdial) through the dialysis liquid fluid line, and a fluid removal rate (Qpfr) from the patient,
- display on the user interface a first indicium prompting a user to select whether to enter in a dose control mode,
- display on the user interface a second indicium prompting the user to select a treatment mode including at least one of ultrafiltration, hemofiltration, hemodialysis, and hemodiafiltration,
- receive a selection to enter in the dose control mode and a selected treatment mode in response to the first and second indiciums,
- determine whether the selected treatment mode and the dose control mode are conflicting, and
- prevent entering in the dose control mode in response to a determined conflict between the selected treatment mode and the dose control mode.
16 more elements
Dependencies are inferred from the claim text.