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US 2020/0345901 A1Published application
Kits for local delivery of water soluble agents and methods of use
AssigneeMedtronic, Inc.
InventorsXiangji Chen, Satish Pulapura
Life of this patent
Estimating the term…
Abstract
A kit includes a mesh substrate and a polymer that is fixed to the mesh substrate. The polymer includes an active agent that is configured to elute over time. The kit further includes a hemostatic agent. The hemostatic agent is separate from the mesh substrate and the polymer. Systems and methods are disclosed.
Claims21
1-20. (canceled)
A kit comprising:
- a substrate consisting of collagen;
- a coating that covers at least a portion of the substrate;
- and
- a hemostatic agent,
- wherein the substrate with the coating is disposed in a first package and the hemostatic agent is disposed in a second package that is separate from the first package.
2 more elements
A kit comprising:
- an implantable medical device selected from the group consisting of cardiac monitors, defibrillators, pacemakers and left ventricle assist devices;
- a substrate consisting of collagen, the substrate comprising a pocket configured for disposal of the implantable medical device;
- a tyrosine-derived polyesteramide polymer that covers at least a portion of the substrate, the polymer having a combination of minocycline and rifampin dispersed therein;
- and
- tranexamic acid, the tranexamic acid being provided in a solution,
- wherein the substrate with the polymer and the implantable medical device are disposed in a first package and the hemostatic agent is disposed in a second package that is separate from the first package.
3 more elements
A kit comprising:
- an implantable medical device selected from the group consisting of cardiac monitors, defibrillators, pacemakers and left ventricle assist devices;
- a substrate consisting of collagen, the substrate comprising a pocket configured for disposal of the implantable medical device;
- a tyrosine-derived polyesteramide polymer that covers at least a portion of the substrate, the polymer having a combination of minocycline and rifampin dispersed therein;
- and
- tranexamic acid, the tranexamic acid being provided in a solution,
- wherein the substrate with the polymer is disposed in a first package, the hemostatic agent is disposed in a second package that is separate from the first package and the implantable medical device is disposed in a third package that is separate from the first package and the second package.
3 more elements
Dependencies are inferred from the claim text.