Back to results
US 2020/0345828 A1Published application
Norovirus vaccine
AssigneeOlogy Bioservices, Inc.
InventorsRON COBB, MICHAEL SPRINGER, YAWEI NI
Life of this patent
Estimating the term…
Loading patent…
Loading patent…
AssigneeOlogy Bioservices, Inc.
InventorsRON COBB, MICHAEL SPRINGER, YAWEI NI
Estimating the term…
A dry powder norovirus vaccine is provided, which comprises at least two norovirus antigens representing different genogroups. The vaccine may be produced by formulation with a mixture of different antigens or combination of monovalent powders with each containing one antigen. The formulated vaccine is suitable for mucosal administration and soluble in aqueous solutions for parenteral administration. A method of immunization is also provided, which comprises at least one administration of the vaccine via mucosal and/or parental route. The immunization may have multiple administrations of the vaccine, i.e., one or more immunizations via a mucosal route followed by one or more immunizations via a parenteral route or vice versa, to maximize both mucosal and systemic immune responses and protection against norovirus infections.
A method of immunizing a mammalian subject against a norovirus infection with a multivalent norovirus dry powder vaccine composition adapted to mucosal and parental administration comprising a norovirus VLP antigen of GI genotype, a norovirus VLP antigen of GII genotype, and an anionic polysaccharide, the method comprising:
A method for producing a multivalent dry powder norovirus vaccine composition suitable for both parenteral and mucosal routes of administration comprising:
Dependencies are inferred from the claim text.