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AssigneeThe Crown in Right of the State of New South Wales Acting through The Department of Primary Industri
InventorsStephen Roger Graves, John Stenos, Moira Cecelia Graves, Rudolf Toman, Rodney Carbis
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Vaccines and methods are for immunization against Coxiella burnetii infections and Q fever. The vaccine can be for protection against a Coxiella burnetii infection, or treating or preventing at least one symptom of Q fever. The vaccine includes a delipidated C. burnetii polysaccharide derived from a cell wall lipopolysaccharide of C. burnetii. The vaccine can also be a conjugate vaccine for protection against a Coxiella burnetii infection, or treating or preventing at least one symptom of Q fever. The conjugate vaccine includes a delipidated C. burnetii polysaccharide derived from a cell wall lipopolysaccharide of C. burnetii linked to an immunogenic carrier.
A vaccine for protection against a Coxiella burnetii infection, the vaccine comprising a delipidated C. burnetii polysaccharide derived from a cell wall lipopolysaccharide of C. burnetii, wherein the delipidated polysaccharide is derivatized.
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A conjugate vaccine for protection against a Coxiella burnetii infection, the vaccine comprising a delipidated C. burnetii polysaccharide derived from a cell wall lipopolysaccharide of C. burnetii linked to an immunogenic carrier, wherein the delipidated polysaccharide is derivatized.
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A method for protecting a subject against a Coxiella burnetii infection or for treating or preventing at least one symptom of Q fever, the method comprising administering to the subject an immunoprotective amount of a vaccine comprising a derivatized delipidated C. burnetii polysaccharide derived from a cell wall lipopolysaccharide of C. burnetii, optionally linked to an immunogenic carrier.
Dependencies are inferred from the claim text.