Compositions and methods useable for treatment of dry eye
AssigneeAllegro Ophthalmics, LLC
InventorsHampar L. Karageozian, John Y. Park, Vicken H. Karageozian, Melvin Arbis Sarayba, Lisa S. Karageozian, Janine M. Aubel
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Abstract
Compositions and methods for treating Dry Eye in a human or non-human animal subject wherein an effective amount of a pharmaceutical composition comprising an anti-integrin peptide is administered to an eye of the subject. The anti-integrin peptide may comprise a peptide which causes at least one effect selected from: reduced expression of the Complement 3 Receptor (Integrin αMβ2); reduced leucocyte adhesion; and reduced trans-endothelial leucocyte migration. The peptide may comprises Risuteganib.
Claims25
A method for treating Dry Eye in a subject in need thereof, said method comprising the step of administering to the subject an effective amount of a pharmaceutical composition comprising an anti-integrin peptide.
A method according to 3 wherein the pharmaceutical composition comprises 0.05 to 5.0% by weight Risuteganib.
-47. (canceled)
Dependencies are inferred from the claim text.