Method for treating thalassemia
AssigneeSt. Jude Children's Research Hospital
InventorsMitchell J. Weiss, Mondira Kundu, Christophe Lechauve
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Abstract
Methods for removing excess free α-globin in erythroid cells and treating a thalassemia using an agent that activates Unc-51 Like autophagy activating Kinase (ULK) are described.
Claims7
A method for removing excess free α-globin in erythroid cells comprising contacting erythroid cells with an effective amount of an agent that activates Unc-51 Like autophagy activating Kinase (ULK) thereby removing excess free α-globin in the erythroid cells.
A method for treating a thalassemia comprising administering to a subject in need thereof an effective amount of an agent that activates Unc-51 Like autophagy activating Kinase (ULK) thereby treating the subject's thalassemia.
Dependencies are inferred from the claim text.